IONS
Ionis Pharmaceuticals, Inc.
Ionis Pharmaceuticals is a biopharmaceutical company focused on RNA-targeted therapeutics, with its sole political signal being a disclosed dividend-generating stock holding by former President Donald J. Trump.
Govt Dependence
5/100
Regulatory Density
85/100
Lobbying Intensity
0/100
Political Signal
NEUTRAL
BusinessWhat IONS does
Ionis Pharmaceuticals develops and commercializes RNA-targeted therapeutics, primarily for rare diseases. Its revenue is derived from collaborative R&D agreements, royalties, and product sales from partnered and wholly-owned drugs. The company's pipeline is heavily dependent on clinical trial outcomes and regulatory approvals from agencies like the FDA.
12 months past · 3 months futureIONS activity timeline
Congress
buy
sell
Insider · Form 4
open-market buy
Hedge fund · 13F
opened
+ added
− trimmed
closed
holds
Bills
past action (this ticker)
upcoming markup (sector)
★ carveout (this ticker)
248 trading days ·
0 congressional trades shown
·
0 insider buys
·
14 13F filings
·
3 past bill actions
·
3 upcoming markups
Executive Branch ConflictsIONS held by Trump-administration officials
1 cabinet/senior official reported IONS positions in OGE Form 278 disclosures across 1 filings.
Lifetime Government AwardsIONS federal contracts by year
$6M
total awarded · 2004–2005
2
contracts on file
2004
peak year ($6M)
Top contracts by award amount
$5.6M
Department of Health and Human Serv
2004-09-30
ASSESSING THE SAFETY OF CELL SUBSTRATES AND VACCINE COMPONENTS
$706K
Department of Defense
2005-04-14
2 years · 2 contracts
Smart Money · 13F HoldingsHedge funds holding IONS
$463.02B
Total IONS held by tracked 13F funds
6
Funds with IONS positions
Two Sigma Investments
$439.85B
-71%
2026-03-31
Renaissance Technologies
$22.94B
+37%
2026-03-31
Citadel Advisors
$165M
-13%
2025-12-31
D.E. Shaw & Co.
$35M
+7729%
2025-12-31
D.E. Shaw & Co.
$26M
-99%
2025-12-31
Bridgewater Associates
$5M
+55%
2025-12-31
Congressional TradesWho in Congress is trading IONS
2023-03-06
Daniel S. Goldman
Sale
$1,001 - $15,000
2023-03-06
Daniel S. Goldman
sale
$1,001 - $15,000
2023-03-14
Ro Khanna
Sale
$1,001 - $15,000
2023-03-14
Ro Khanna
sale
$1,001 - $15,000
2023-01-04
Ro Khanna
Exchange
$1,001 - $15,000
2023-01-04
Ro Khanna
exchange
$1,001 - $15,000
2019-05-08
(unknown)
purchase
$1,001 - $15,000
355d late
2019-06-24
(unknown)
sale
$1,001 - $15,000
308d late
2019-06-24
(unknown)
Sale
$1,001 - $15,000
308d late
2019-05-08
(unknown)
Purchase
$1,001 - $15,000
355d late
2019-04-29
Ro Khanna
sale
$1,001 - $15,000
2019-04-29
Ro Khanna
Sale
$1,001 - $15,000
26+ trades on file · most recent 2023-04-17
Corporate Insiders · Form 4What CEOs, CFOs, and directors are doing with their own stock
No Form 4 activity recorded in the last 180 days.
Bills Affecting IONSLive legislation impacting this stock
S.827 · 119th
Supporting Rural Veterans Access to Healthcare Services Act
HR.2001 · 119th
Action for Dental Health Act
HR.1860 · 119th
Women Veterans Cancer Care Coordination Act
HR.2068 · 119th
Veterans Patient Advocacy Act
HR.2020 · 119th
New Mexico Rural Veteran Health Care Access Act
S.999 · 119th
Public Health Improvement Act
HR.2062 · 119th
To amend the Internal Revenue Code of 1986 to treat membership in a health care sharing ministry as a medical expense, and for oth
HR.2085 · 119th
Mental Health Research Accelerator Act of 2025
HR.2045 · 119th
Medicare Dental, Vision, and Hearing Benefit Act of 2025
HR.2048 · 119th
Metastatic Breast Cancer Access to Care Act
Political ProfileWhere IONS sits in Washington
[object Object]
STRUCTURAL: No lobbying spend (`get_political_influence.lobbying.total_income: 0`), no donations, and no federal contracts (`get_government_precedent.federal_contracts_summary: null`). EVIDENTIARY: One executive branch holding (`get_executive_branch_exposure.by_ticker[0].holdings[0].filer: Donald J. Trump`) with minimal reported value ('None (or less than $1,001)'), zero corporate insider buys in 180 days (`get_corporate_insider_signal.total_buys: 0`), and zero congressional traders. Net: Minimal direct political footprint.
Regulatory ExposureThreats & opportunities
Regulatory threats
-
General legislative pressure on drug pricing and reimbursementCongress, HHS"Eight recent healthcare bills identified in `Recent bill_impacts` with non-zero impact_ratios."
Regulatory opportunities
-
Potential for favorable orphan drug or accelerated approval pathwaysFDA"Inferred from primary industry and sector, but no specific carveouts in `Recent bill_carveouts`."
Member intelligence layer
Live signals + predictions for IONS — for Founders
The free page above gives you the public record. Members see the real-time intelligence layer on top of it:
- Live 7-layer signal scores when Congress trades IONS
- Bill Pass Index v2 odds for every bill on the watch list
- Iron Triangle alerts (committee × donor × trade)
- SEC Form 4 cluster detection (CEO + CFO + director buys)
- Whale-Opportunity expected-value ranking
- Custom watchlist alerts via email + Discord
Frequently AskedAbout IONS & political exposure
Does Ionis Pharmaceuticals, Inc. (IONS) hold federal contracts?
Yes. Ionis Pharmaceuticals, Inc. has 2 federal contract awards totaling $6,319,623, primarily from agencies including Department of Defense, Department of Health and Human Services. See full contract list and amounts on this page.
Which Trump cabinet officials own IONS stock?
1 Trump cabinet members or senior White House staff have disclosed holdings in IONS on their OGE 278 financial disclosures, including Donald J. Trump. See the Cabinet Conflicts panel for details.
Has Congress traded IONS stock?
26 congressional trades by 5 unique members of Congress, most recently on 2023-03-14. See the Congressional Trading panel for politician-by-politician breakdown.
What is IONS political risk profile?
Government dependence: 5/100. Lobbying intensity: 0/100. Political signal: neutral. Donor party split: R 0% / D 0%.
How does GovGreed track IONS political activity?
GovGreed integrates STOCK Act congressional trade disclosures, FEC contributions, OGE executive-branch disclosures, USASpending federal contracts, Senate LDA lobbying filings, and SEC Form 4 corporate insider trades into a single queryable graph. IONS data is updated daily from these official federal sources.