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AGIO

Agios Pharmaceuticals, Inc.

Sector: pharmaBiotechnologyNASDAQMarket Cap: $2.01B

Agios Pharmaceuticals is a biopharmaceutical company focused on cellular metabolism and rare genetic diseases, with its strongest political signal being $1.5M in annual doctor payments and two congressional purchases by a single member.

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Govt Dependence
5/100
Regulatory Density
85/100
Lobbying Intensity
0/100
Political Signal
NEUTRAL

BusinessWhat AGIO does

Agios Pharmaceuticals develops and commercializes medicines for rare genetic diseases, particularly in hematology and oncology, with revenue derived from product sales and collaborations. Its pipeline includes treatments for pyruvate kinase deficiency and other metabolic disorders. The company operates in a highly regulated FDA environment with no federal contract revenue.

12 months past · 3 months futureAGIO activity timeline

$47$34$22 OctNovDecJan '26FebMarAprMayJunJulAugSepOctNovDec ↓ PAST — recorded activity ↑ FUTURE — scheduled markups · pending votes TODAY · Sep 14 $45.49 hi $22.34 lo $33.13 CONGRESS 17 INSIDERS 0 13F FUNDS 24 BILLS 26 Gilbert Ray Cisneros (D) · Purchase · 2026-08-20Gilbert Ray Cisneros (D) · Purchase · 2026-03-03Gilbert Ray Cisneros (D) · Purchase · 2025-12-11 Two Sigma Investments · - $8513M · 2026-03-31D.E. Shaw & Co. · + $37M · 2025-12-31Citadel Advisors · + $29M · 2025-12-31Citadel Advisors · - $17M · 2025-09-30D.E. Shaw & Co. · - $11M · 2025-09-30Two Sigma Investments · + $8M · 2025-12-31Two Sigma Investments · OPENED $2M · 2025-09-30 S.1387 · committee · 2026-03-19 MARKUP · Senate Health, Education, Labor, and Pensions · 2026-09-16
Congress
buy sell
Insider · Form 4
open-market buy
Hedge fund · 13F
opened + added − trimmed closed holds
Bills
past action (this ticker) upcoming markup (sector) carveout (this ticker)
245 trading days · 3 congressional trades shown · 0 insider buys · 7 13F filings · 1 past bill actions · 1 upcoming markups

Lifetime Government AwardsAGIO federal contracts

AGIO doesn't hold direct federal contracts.

Verified via USASpending.gov: $0 reported in direct prime-contract awards. Companies in this position typically sell federal services indirectly through prime contractors and integrators (e.g., Lockheed Martin, Booz Allen, Microsoft Azure) or through commercial channels that don't appear in USASpending data.

Smart Money · 13F HoldingsHedge funds holding AGIO

$8.58B
Total AGIO held by tracked 13F funds
3
Funds with AGIO positions
Two Sigma Investments $8.51B -16% 1 overlap 2026-03-31
D.E. Shaw & Co. $37M +378% 1 overlap 2025-12-31
Citadel Advisors $29M +143% 1 overlap 2025-12-31

Politicians Trading AGIOMembers of Congress with recent AGIO positions

1 politicians traded AGIO across 7 disclosed transactions totaling $56K (last 730 days). Greed score = composite of trade frequency, volume & recency across the politician's entire history (not just AGIO). 0-30 LOW · 30-60 MID · 60+ HIGH.

Congressional TradesWho in Congress is trading AGIO

2026-08-20 Gilbert Ray Cisneros D-California · house Purchase $1,001 - $15,000
2026-03-03 Gilbert Ray Cisneros D-California · house Purchase $1,001 - $15,000
2025-12-11 Gilbert Ray Cisneros D-California · house Purchase $1,001 - $15,000
2025-04-17 Gilbert Ray Cisneros D-California · house Purchase $1,001 - $15,000
2025-04-17 Gilbert Ray Cisneros D-California · house purchase $1,001 - $15,000
2025-01-29 Gilbert Ray Cisneros D-California · house purchase $1,001 - $15,000
2025-01-29 Gilbert Ray Cisneros D-California · house Purchase $1,001 - $15,000
2024-01-24 Josh Gottheimer D-New Jersey · house Purchase $1,001 - $15,000
2024-01-24 Josh Gottheimer D-New Jersey · house purchase $1,001 - $15,000
2018-10-25 Ro Khanna D-California · house Sale $1,001 - $15,000
2018-10-25 Ro Khanna D-California · house sale $1,001 - $15,000
2018-04-03 Ro Khanna D-California · house Purchase $1,001 - $15,000
17+ trades on file · most recent 2026-09-11

Corporate Insiders · Form 4What CEOs, CFOs, and directors are doing with their own stock

No Form 4 activity recorded in the last 180 days.

Bills Affecting AGIOLive legislation impacting this stock

Political ProfileWhere AGIO sits in Washington

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STRUCTURAL: High regulatory density from 8 pharma bills (impact_ratios 0.0088-0.0114) and $1.5M annual doctor payments (get_political_influence.doctor_payments). EVIDENTIARY: Two congressional purchases by one member (bioguide_id C001123) but no corporate insider buys (get_corporate_insider_signal.total_buys: 0). Net: Moderate regulatory exposure with weak transactional signals.

Regulatory ExposureThreats & opportunities

Regulatory threats

  • High regulatory density from FDA oversight and potential legislative impacts
    FDA, Congress
    "Recent bill_impacts array shows 8 pharma bills with impact_ratios up to 0.0114"

Regulatory opportunities

  • Potential for orphan drug designations and expedited reviews
    FDA
    "Sector is pharma with rare disease focus, but no specific carveouts in bill_carveouts array"

Capitol Hill AlliesChampions & critics

Congressional champions

Congressional critics

  • No specific congressional critics identified.
Member intelligence layer

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Frequently AskedAbout AGIO & political exposure

Does Agios Pharmaceuticals, Inc. (AGIO) hold federal contracts?
No direct prime contracts reported in USASpending.gov for Agios Pharmaceuticals, Inc.. Companies in the semiconductor and AI hardware sectors often sell to the federal government via prime contractors and cloud resellers (Microsoft Azure, AWS, Lockheed Martin systems integration) rather than as direct primes.
Has Congress traded AGIO stock?
17 congressional trades by 4 unique members of Congress, most recently on 2026-08-20. See the Congressional Trading panel for politician-by-politician breakdown.
What is AGIO political risk profile?
Government dependence: 5/100. Lobbying intensity: 0/100. Political signal: neutral. Donor party split: R 0% / D 0%.
How does GovGreed track AGIO political activity?
GovGreed integrates STOCK Act congressional trade disclosures, FEC contributions, OGE executive-branch disclosures, USASpending federal contracts, Senate LDA lobbying filings, and SEC Form 4 corporate insider trades into a single queryable graph. AGIO data is updated daily from these official federal sources.