Nitazene Response Act

119 HR 8192 IH: Nitazene Response Act U.S. House of Representatives 2026-04-02 text/xml EN Pursuant to Title 17 Section 105 of the United States Code, this file is not subject to copyright protection and is in the public domain. I 119th CONGRESS 2d Session H. R. 8192 IN THE HOUSE OF REPRESENTATIVES April 2, 2026 Mr. Taylor introduced the following bill; which was referred to the Committee on Energy and Commerce A BILL To direct the Secretary of Health and Human Services to issue guidelines for the purpose of addressing the problem of nitazene overdoses, and for other purposes. 1. Short title This Act may be cited as the Nitazene Response Act . 2. Assistance in responding to nitazene overdoses (a) Guidelines (1) In general The Secretary of Health and Human Services (in this section referred to as the Secretary ) shall issue updated, evidence-based clinical guidelines (in this section referred to as the guidelines ) for responding to nitazene overdoses. (2) Contents The guidelines shall contain— (A) a description of best practices for responding to potential nitazene overdoses, including protocols for administering naloxone; (B) guidance for emergency departments and hospitals in responding to nitazene overdoses; (C) guidance for rural and volunteer emergency medical services systems in responding to nitazene overdoses; and (D) such other information as the Secretary determines appropriate. (3) Publication Not later than 180 days after the date of enactment of this Act, the Secretary shall publish the guidelines on the public internet website of the Department of Health and Human Services. (b) Report to Congress Not later than one year after the date of enactment of this Act, the Secretary shall submit to Congress a report containing the guidelines and a description of how the guidelines will assist in addressing the problem of nitazene overdoses. (c) Definitions In this section: (1) Nitazene (A) In general The term nitazene means benzimidazole-opioids, including any substance (including its salts, isomers, and salts of isomers) that has a chemical structure that is substantially similar to that of etonitazene or isotonitazene, including— (i) a benzimidazole core substituted at the 2-position with a benzyl or substituted benzyl group; (ii) a basic nitrogen-containing side chain at the 1-position; and (iii) exhibits agonist activity at the mu-opioid receptor. (B) Included substances The term nitazene includes, at a minimum, the following: etonitazene, clonitazene, metonitazene, isotonitazene, protonitazene, butonitazene, etodesnitazene, flunitazene, N-pyrrolidino etonitazene, N-desethyl isotonitazene, and N-piperidinyl etonitazene. (2) Nitazene overdose The term nitazene overdose means an overdose involving nitazene or any other ultra-potent synthetic opioid.